VarElect Phenotype-driven Analysis

TGex uses VarElect, the Next Generation Sequencing Phenotyper, to score and prioritize variant-genes based on disease/phenotype of interest.

VarElect's interpretation engine leverages the GeneCards Suite Knowledgebase's powerful free text search engine, allowing for any phenotype to be entered, and ranking variants according to their association to the desired phenotype. This association is also supplemented by providing evidence for each association, which can further be investigated through direct access to more details in GeneCards, the Human Gene Database, and MalaCards, the Human Disease Database.

VarElect's unique advantage stems from its ability to leverage the extensive data available in the knowledgebase to infer direct, as well as indirect links, between genes and diseases/phenotypes.

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