Knowledge-Driven NGS Analysis

The GeneCards Suite-powered end-to-end NGS analysis and interpretation platform

Rapid Analysis, Interpretation & Reporting From VCF to Report in Minutes.

Powered by the GeneCardsSuite

Integrating > 120 key data sources, the GeneCards® Suite Knowledgebase empowers your Next Generation Sequencing analysis by highlighting associations between genes and phenotypes, providing supporting evidence for immediate evaluation and automatically generating case reports.

Efficient and more accurate analysis

Standardize your analysis pipeline using customizable protocols.

Browse and identify key genetic variants in an easy-to-use, powerful user interface with flexible and interactive filters and annotations.

Analyze any combination of samples – rare disorders (single and family), cancer (tumor and tumor-germline) and more.

TGex helps you be a better analyst.

Read more

Customizable Evidence-Driven Reports

Spend less time collecting evidence by leveraging TGex’s automatic and customizable reporting.

Once you have selected key variants in your analysis, you’re only two clicks away from getting a full report with all relevant annotations, evidence and publications. It’s that simple.


TGex generates the report for you.

Read more

Available Anywhere

Cloud & On Premise

TGex can be deployed on the cloud or on premises, providing you with the freedom to choose how and where you work.

When installed within your firewall, integrate it with your commercial databases and internal and external data sources. Create your own in-house proprietary database based on your own sequencing data.

TGex makes it easy for you to scale up your NGS core capabilities.

Read more


Having analyzed hundreds of cancer cases using NGS, I've found TGex to be a great tool for evaluating variants and analyzing multiple samples like tumor-germline pairs or familial cases. TGex clearly significantly boosts the access of relevant information for the translation of the genomic information into clinical decision making. Furthermore, the user interface is comfortable, highly flexible and interactive, and reduces the time invested in each analysis. Altogether, I highly recommend TGex as a platform for analysis of cancer cases, and as a tool to preparing a report of genomic information to be provided to clinical care professionals.

Prof. Izhak Haviv, Ph.D.

Head, Cancer Personalized Medicine & Diagnostic Genomics
Faculty of Medicine, Bar Ilan University

I have had the pleasure of working with VarElect and TGex... which have an uncanny ability in discovering the right “culpable” variant in complex cases studied with whole exome sequence (WES)... both these programs have been extremely useful in our WES analyses. They are simple to use and yet most efficient. Thus, I recommend them very strongly.

Prof. Sergio D.J. Pena, MD, PhD, FRCP(C)

Professor, Department of Biochemistry and Immunology
Universidade Federal de Minas Gerais

TGex is an easy-to-use system for managing our genetic tests. It makes it easy to identify variants of relevance through its integration with various sources of evidence, and its ability to customize reports allows us to present our results to clients in the most useful manner. We strongly recommend it for labs that provide genetic information to clinical care professionals.

Lina Abi Mosleh, Ph.D.

Principal Scientist
Ayass BioScience, Inc.

Dvir Dahary, Yaron Golan, Yaron Mazor, Ofer Zelig, Ruth Barshir, Michal Twik, Tsippi Iny Stein, Guy Rosner, Revital Kariv, Fei Chen, Qiang Zhang, Yiping Shen, Marilyn Safran, Doron Lancet & Simon Fishilevich
Genome analysis and knowledge-driven variant interpretation with TGex,
BMC Med Genomics 12, 200 (2019)  [PDF]

Start Analyzing Your NGS Data

Start for free